For all of you who, like me,
are new to this field, a brief description of both conservation genetics and
genomics would come in handy. According to Ouborg et al. (2010), conservation
genetics is characterized by assessing relationships between population size
and neutral sequence variation. But, what is neutral sequence variation? Well,
there is a theory called The Neutral Theory of Molecular Evolution; it will
help us understand what neutral variation is.
According to The Neutral
Theory of Molecular Evolution, the vast Majority of evolutionary changes at the
molecular level are caused by random drift of selectively neutral mutants which
do not affect fitness, therefore referred to as neutral. [1]
On the other hand,
conservation genomics assesses relationships between population size and both
neutral and selectively important variation, both in terms of sequence
variation and gene expression variation, and thereby incorporates potential
effects of selection. Conservation genomics also incorporates the influence of
environmental conditions on sequence variation (via selection) and on gene
expression variation. [2]
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[2] |
References:
[1] Kimura, M (1983). The neutral theory of molecular
evolution. Cambridge (page xi)
[2] Ouborg NJ, Pertoldi C, Loeschcke V, Bijlsma R,
Hedrick PW (2010). Conservation genetics in transition to conservation
genomics. Trends Genet 26: 177-187. http://dx.doi.org/10.1016/j.tig.2010.01.001
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